Publications

Some of our work featured on the front cover of journals:

The following list displays the lab’s most recent papers. For a full list of publications, please see Pubmed.

  1. Reilly, RB, Ramdour, SK, Fuhlbrigge, ME, Tavares, LP, Staffa, SJ, Booth, JM et al.. An altered natural killer cell immunophenotype characterizes clinically severe pediatric RSV infection. Sci Transl Med. 2024;16 (768):eado6606. doi: 10.1126/scitranslmed.ado6606. PubMed PMID:39383246 .
  2. Serhan, CN, Levy, BD. Proresolving Lipid Mediators in the Respiratory System. Annu Rev Physiol. 2024; :. doi: 10.1146/annurev-physiol-020924-033209. PubMed PMID:39303274 .
  3. Xu, W, Hong, YS, Hu, B, Comhair, SAA, Janocha, AJ, Zein, JG et al.. Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations. J Allergy Clin Immunol. 2024; :. doi: 10.1016/j.jaci.2024.08.022. PubMed PMID:39237012 .
  4. Brüggemann, TR, Krishnamoorthy, N, Hagner, M, Matschiner, G, Jaquin, T, Tavares, LP et al.. A new Anticalin protein for IL-23 inhibits non-type 2 allergen-driven mouse lung inflammation and airway hyperresponsiveness. Am J Physiol Lung Cell Mol Physiol. 2024;327 (5):L624-L633. doi: 10.1152/ajplung.00295.2023. PubMed PMID:39104317 PubMed Central PMC11563638.
  5. Peh, HY, Nshimiyimana, R, Brüggemann, TR, Duvall, MG, Nijmeh, J, Serhan, CN et al.. 15-epi-lipoxin A5 promotes neutrophil exit from exudates for clearance by splenic macrophages. FASEB J. 2024;38 (14):e23807. doi: 10.1096/fj.202400610R. PubMed PMID:38989570 PubMed Central PMC11344644.
  6. Liegeois, MA, Braunreuther, M, Charbit, AR, Raymond, WW, Tang, M, Woodruff, PG et al.. Peroxidase-mediated mucin cross-linking drives pathologic mucus gel formation in IL-13-stimulated airway epithelial cells. JCI Insight. 2024;9 (15):. doi: 10.1172/jci.insight.181024. PubMed PMID:38889046 PubMed Central PMC11383604.
  7. Everman, JL, Sajuthi, SP, Liegeois, MA, Jackson, ND, Collet, EH, Peters, MC et al.. A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma. Nat Commun. 2024;15 (1):3900. doi: 10.1038/s41467-024-48034-5. PubMed PMID:38724552 PubMed Central PMC11082194.
  8. Tang, M, Charbit, AR, Johansson, MW, Jarjour, NN, Denlinger, LC, Raymond, WW et al.. Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma. J Allergy Clin Immunol. 2024;154 (3):580-591.e6. doi: 10.1016/j.jaci.2024.03.023. PubMed PMID:38663815 .
  9. Charbit, AR, Liegeois, MA, Raymond, WW, Comhair, SAA, Johansson, MW, Hastie, AT et al.. A novel DNase assay reveals low DNase activity in severe asthma. Am J Physiol Lung Cell Mol Physiol. 2024;326 (6):L796-L804. doi: 10.1152/ajplung.00081.2024. PubMed PMID:38651338 PubMed Central PMC11380938.
  10. Kilic, A, Halu, A, De Marzio, M, Maiorino, E, Duvall, MG, Bruggemann, TR et al.. Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1. Elife. 2024;12 :. doi: 10.7554/eLife.89270. PubMed PMID:38567749 PubMed Central PMC10990493.
  11. Liu, T, Liu, S, Rui, X, Cao, Y, Hecker, J, Guo, F et al.. Gasdermin B, an asthma-susceptibility gene, promotes MAVS-TBK1 signalling and airway inflammation. Eur Respir J. 2024;63 (5):. doi: 10.1183/13993003.01232-2023. PubMed PMID:38514093 PubMed Central PMC11063620.
  12. Hastie, AT, Bishop, AC, Khan, MS, Bleecker, ER, Castro, M, Denlinger, LC et al.. Protein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma. Clin Exp Allergy. 2024;54 (4):265-277. doi: 10.1111/cea.14447. PubMed PMID:38253462 PubMed Central PMC11075125.
  13. Huang, BK, Elicker, BM, Henry, TS, Kallianos, KG, Hahn, LD, Tang, M et al.. Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma. JCI Insight. 2024;9 (3):. doi: 10.1172/jci.insight.174124. PubMed PMID:38127464 PubMed Central PMC10967478.
  14. Leung, C, Tang, M, Huang, BK, Fain, SB, Hoffman, EA, Choi, J et al.. A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma. Am J Respir Crit Care Med. 2024;209 (10):1196-1207. doi: 10.1164/rccm.202305-0802OC. PubMed PMID:38113166 PubMed Central PMC11146546.
  15. Xu, W, Hong, YS, Hu, B, Comhair, SAA, Janocha, AJ, Zein, JG et al.. Mitochondrial DNA Copy Number Variation in Asthma Risk, Severity, and Exacerbations. medRxiv. 2023; :. doi: 10.1101/2023.12.05.23299392. PubMed PMID:38106101 PubMed Central PMC10723502.
  16. Wada, N, Li, Y, Gagne, S, Hino, T, Valtchinov, VI, Gay, E et al.. Incidence and severity of pulmonary embolism in COVID-19 infection: Ancestral, Alpha, Delta, and Omicron variants. Medicine (Baltimore). 2023;102 (48):e36417. doi: 10.1097/MD.0000000000036417. PubMed PMID:38050198 PubMed Central PMC10695578.
  17. Peh, HY, Brüggemann, TR, Duvall, MG, Nshimiyimana, R, Nijmeh, J, Cinelli, MA et al.. Resolvin D2 regulates type 2 inflammatory responses and promotes resolution of mouse allergic inflammation. Allergy. 2024;79 (3):739-743. doi: 10.1111/all.15920. PubMed PMID:37888888 PubMed Central PMC10922258.
  18. Tavares, LP, Nijmeh, J, Levy, BD. Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators. Exp Biol Med (Maywood). 2023;248 (19):1635-1644. doi: 10.1177/15353702231199082. PubMed PMID:37837390 PubMed Central PMC10723024.
  19. Brüggemann, TR, Peh, HY, Tavares, LP, Nijmeh, J, Shay, AE, Rezende, RM et al.. Eosinophil Phenotypes Are Functionally Regulated by Resolvin D2 during Allergic Lung Inflammation. Am J Respir Cell Mol Biol. 2023;69 (6):666-677. doi: 10.1165/rcmb.2023-0121OC. PubMed PMID:37552821 PubMed Central PMC10704125.
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