Some of our work featured on the front cover of journals:

The following list displays the lab’s most recent papers. For a full list of publications, please see Pubmed.

  1. Hastie, AT, Mauger, DT, Denlinger, LC, Coverstone, A, Castro, M, Erzurum, S et al.. Baseline sputum eosinophil+neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) Cohort. J. Allergy Clin. Immunol. 2020; :. doi: 10.1016/j.jaci.2020.01.039. PubMed PMID:32032631 .
  2. Talbot, S, Doyle, B, Huang, J, Wang, JC, Ahmadi, M, Roberson, DP et al.. Vagal sensory neurons drive mucous cell metaplasia. J. Allergy Clin. Immunol. 2020; :. doi: 10.1016/j.jaci.2020.01.003. PubMed PMID:31954778 .
  3. Jundi, B, Ryu, H, Lee, DH, Abdulnour, RE, Engstrom, BD, Duvall, MG et al.. Leukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity. Nat Biomed Eng. 2019;3 (12):961-973. doi: 10.1038/s41551-019-0473-5. PubMed PMID:31712645 PubMed Central PMC6899180.
  4. Levy, BD, Abdulnour, RE, Tavares, A, Brüggemann, TR, Norris, PC, Bai, Y et al.. Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes. J. Allergy Clin. Immunol. 2020;145 (1):335-344. doi: 10.1016/j.jaci.2019.09.028. PubMed PMID:31622689 .
  5. Wallrapp, A, Burkett, PR, Riesenfeld, SJ, Kim, SJ, Christian, E, Abdulnour, RE et al.. Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses. Immunity. 2019;51 (4):709-723.e6. doi: 10.1016/j.immuni.2019.09.005. PubMed PMID:31604686 .
  6. Fitzpatrick, AM, Szefler, SJ, Mauger, DT, Phillips, BR, Denlinger, LC, Moore, WC et al.. Development and initial validation of the Asthma Severity Scoring System (ASSESS). J. Allergy Clin. Immunol. 2020;145 (1):127-139. doi: 10.1016/j.jaci.2019.09.018. PubMed PMID:31604088 PubMed Central PMC6949388.
  7. Vallurupalli, M, Divakaran, S, Parnes, A, Levy, BD, Loscalzo, J. The Element of Surprise. N. Engl. J. Med. 2019;381 (14):1365-1371. doi: 10.1056/NEJMcps1811547. PubMed PMID:31577880 .
  8. Tavares, AH, Colby, JK, Levy, BD, Abdulnour, RE. A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation. J Vis Exp. 2019; (150):. doi: 10.3791/60024. PubMed PMID:31524861 .
  9. Ash, SY, Sanchez-Ferrero, GV, Schiebler, ML, Rahaghi, FN, Rai, A, Come, CE et al.. Estimated Ventricular Size, Asthma Severity, and Exacerbations: The Severe Asthma Research Program III Cohort. Chest. 2020;157 (2):258-267. doi: 10.1016/j.chest.2019.08.2185. PubMed PMID:31521672 PubMed Central PMC7005378.
  10. Li, X, Hastie, AT, Peters, MC, Hawkins, GA, Phipatanakul, W, Li, H et al.. Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma. J. Allergy Clin. Immunol. 2020;145 (1):430-433. doi: 10.1016/j.jaci.2019.08.031. PubMed PMID:31513878 .
  11. Kelly, RS, Chawes, BL, Guo, F, Zhang, L, Blighe, K, Litonjua, AA et al.. The role of the 17q21 genotype in the prevention of early childhood asthma and recurrent wheeze by vitamin D. Eur. Respir. J. 2019;54 (4):. doi: 10.1183/13993003.00761-2019. PubMed PMID:31439681 .
  12. Lachowicz-Scroggins, ME, Dunican, EM, Charbit, AR, Raymond, W, Looney, MR, Peters, MC et al.. Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. Am. J. Respir. Crit. Care Med. 2019;199 (9):1076-1085. doi: 10.1164/rccm.201810-1869OC. PubMed PMID:30888839 PubMed Central PMC6515873.
  13. Wu, W, Bang, S, Bleecker, ER, Castro, M, Denlinger, L, Erzurum, SC et al.. Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. Am. J. Respir. Crit. Care Med. 2019;199 (11):1358-1367. doi: 10.1164/rccm.201808-1543OC. PubMed PMID:30682261 PubMed Central PMC6543720.
  14. Fitzpatrick, AM, Gillespie, SE, Mauger, DT, Phillips, BR, Bleecker, ER, Israel, E et al.. Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J. Allergy Clin. Immunol. 2019;143 (6):2052-2061. doi: 10.1016/j.jaci.2018.11.022. PubMed PMID:30635198 PubMed Central PMC6556425.
  15. Duvall, MG, Krishnamoorthy, N, Levy, BD. Non-type 2 inflammation in severe asthma is propelled by neutrophil cytoplasts and maintained by defective resolution. Allergol Int. 2019;68 (2):143-149. doi: 10.1016/j.alit.2018.11.006. PubMed PMID:30573389 .
  16. Downing, NS, McMullan, CJ, Rennke, HG, Levy, BD, Loscalzo, J. Complements from the Lung. N. Engl. J. Med. 2018;379 (18):1767-1773. doi: 10.1056/NEJMcps1802644. PubMed PMID:30380383 .
  17. Karra, L, Singh Gangwar, R, Shamri, R, Puzzovio, PG, Cohen-Mor, S, Levy, BD et al.. Leukocyte CD300a Contributes to the Resolution of Murine Allergic Inflammation. J. Immunol. 2018;201 (10):2998-3005. doi: 10.4049/jimmunol.1801000. PubMed PMID:30315138 .
  18. Loynes, CA, Lee, JA, Robertson, AL, Steel, MJ, Ellett, F, Feng, Y et al.. PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo. Sci Adv. 2018;4 (9):eaar8320. doi: 10.1126/sciadv.aar8320. PubMed PMID:30191175 PubMed Central PMC6124908.
  19. Krishnamoorthy, N, Douda, DN, Brüggemann, TR, Ricklefs, I, Duvall, MG, Abdulnour, RE et al.. Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma. Sci Immunol. 2018;3 (26):. doi: 10.1126/sciimmunol.aao4747. PubMed PMID:30076281 PubMed Central PMC6320225.
  20. Abdulnour, RE, Gunderson, T, Barkas, I, Timmons, JY, Barnig, C, Gong, M et al.. Early Intravascular Events Are Associated with Development of Acute Respiratory Distress Syndrome. A Substudy of the LIPS-A Clinical Trial. Am. J. Respir. Crit. Care Med. 2018;197 (12):1575-1585. doi: 10.1164/rccm.201712-2530OC. PubMed PMID:29782179 PubMed Central PMC6006404.
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