Levy Lab Ongoing Research Support
Title: Specialized Pro-Resolving Mediators in Asthma
Major Goals: The major goals of this project are to determine the regulated biosynthesis of specialized pro-resolving mediators by the lung during allergic airway inflammation, and to identify innate immune effector mechanisms for these mediators to limit adaptive inflammation, and dysregulation of these protective mechanisms during viral infection in the setting of asthma exacerbation.
Status of Support: Active
Project Number: 1R01HL122531
Name of PD/PI: Levy, B. (PI)
Source of Support: NIH/NHLBI
Primary Place of Performance: BWH
Project/Proposal Start and End Date: 08/20/2021-05/31/2025
Title: Integrative Training in Respiratory Research
Major Goals: The major goals of this training grant are to provide optimal research infrastructure and environment for lung research trainees.
Status of Support: Active
Project Number: T32HL007633
Name of PD/PI: Levy, B. (PI)
Source of Support: NIH/NHLBI
Primary Place of Performance: BWH
Project/Proposal Start and End Date: 07/01/1985-06/30/2026
Title: Immunometabolic phenotypes in adult severe asthma and disease progression
Major Goals: This is a national, multicenter collaborative study with a mechanistic translational approach with 4 specific aims to rigorously and comprehensively investigate the molecular and cellular origin of SA immunometabolic phenotypes and their relationship to disease progression.
Status of Support: Active
Project Number: 1U01HL146002
Name of PD/PI: Levy, B. (co-PI, Lead contact PI)
Source of Support: NIH/NHLBI
Primary Place of Performance: BWH
Project/Proposal Start and End Date: 09/23/2019 – 06/30/2024
Title: Monitoring pro-resolving leukocyte responses in peripheral blood predicts clinical severity during sepsis
Major Goals: The goals of this grant are to develop an improved understanding of the resolution defects that unleash unrestrained inflammation of sepsis with a longer term goal for new therapeutic targets and prognostic indicators of disease progression.
Status of Support: Active
Project Number: R21GM144829
Name of PD/PI: Levy, B. (co-PI)
Source of Support: NIH/NIGMS
Primary Place of Performance: BWH
Project/Proposal Start and End Date: 12/01/2021 – 11/30/2025
Title: Function and application of lung surfactant proteins
Major Goals: The goals of this project are to perform in vivo structure-function experiments on surfactant proteins in murine acute lung injury.
Status of Support: Active
Project Number: 1R01HL150520
Name of PD/PI: Rapoport, T. PI, Levy B. co-Investigator
Source of Support: NIH/NHLBI
Primary Place of Performance: HMS (BWH subcontract)
Project/Proposal Start and End Date: 02/15/2020 – 1/31/2024
Title: Resolution Mechanisms in Acute Inflammation: Resolution Pharmacology
Status of Support: Active
Project Number: P01 GM095467
Name of PD/PI: Levy, B. (co-PI)
Source of Support: NIH/NIGMS
Primary Place of Performance: BWH
Project/Proposal Start and End Date: 06/01/11 – 03/31/22
Title: RECOVER Cohort Phase II Adult Clinical Recovery Cohort
Major Goals: The goal of the study is to rapidly improve understanding of recovery after SARS-CoV-2 infection and to prevent and treat PASC.
Status of Support: Active
Project Number: 1OT2HL162087-01
Name of PD/PI: Levy, B. (co-PI, Lead contact PI)
Source of Support: NIH/NHLBI
Primary Place of Performance: BWH
Project/Proposal Start and End Date: 08/01/2021 – 07/31/2025
Mentee Career Development Awards:
Rebecca Elaine Cagnina, MD, PhD
- National Heart, Lung, and Blood Institute (NHLBI) K08 HL136903: Regulation of dendritic cell function by neutrophil-derived reactive oxygen species in pulmonary aspergillosis. (5/3/17-4/30/2022)
Melody Duvall, MD, PhD
- National Heart, Lung, and Blood Institute (NHLBI) K08 HL145098: Specialized Pro-Resolving Mediator Regulation of NK Cells in Human RSV Bronchiolitis. (8/1/2019 – 7/31/2023)
- National Institute of Child Health and Human Development (NICHD), Pediatric Critical Care and Trauma Scientist Development Program. K12 HD047349: Unrestrained Natural Killer Cells in Severe Viral Infection Increase Lung Inflammation and Injury
Nandini Krishnamoorthy, PhD
- National Heart, Lung, and Blood Institute (NHLBI), 1R56HL155917-01: Maternal-neonatal transmission of protective resolution mechanisms for lung inflammation (09/10/21 – 08/30/22)
Hong Yong Peh, PhD
- National University of Singapore-Overseas Postdoctoral Fellowship
Luciana Tavares, PhD
- Pew Latin American Fellowship